October 22 coronavirus news | CNN

October 22 coronavirus news

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Wisconsin using overflow facility to keep up with Covid-19 cases
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Data shows Covid-19 treatment remdesivir isn't a "home run," says former vaccine director 

One vial of the drug Remdesivir lies during a press conference at the University Hospital Eppendorf (UKE) in Hamburg, Germany on April 8.

Data on the Covid-19 drug remdesivir show that it has only modest benefits and isn’t a “home run,” former US Health and Human Services official-turned whistleblower Dr. Rick Bright said Thursday.

The US Food and Drug Administration approved remdesivir Thursday to treat hospitalized Covid-19 patients – the first drug to be approved for coronavirus. 

Bright said it’s not an impressive drug.

World Health Organization-sponsored global study found that remdesivir did not help Covid-19 patients survive or recover faster. 

“The FDA clearly has reviewed all of the data that they have available to them from the company to review the efficacy and safety of that drug,” Bright said. 

“It’s not too surprising that another, perhaps even larger, well-controlled study from the WHO would refute that data,” he added.

Bright said that it’s likely that larger studies, like the WHO’s, would show that the marginal benefit of remdesivir may become even more marginal, depending on the population of those using the drug.

Coronavirus outbreak reported at Los Angeles megachurch that defied public health orders

Grace Community Church in Sun Valley, California, as seen on September 4.

A coronavirus outbreak has been reported at a Los Angeles megachurch that has defied the county’s public health orders and held indoor services since August.

The Los Angeles County Department of Public Health on Thursday confirmed three positive cases linked to Grace Community Church in the Sun Valley neighborhood of L.A.’s San Fernando Valley.

Over the past two months, Grace Community Church was cited nine times by the public health department for failing to comply with health officer orders, according to the Los Angeles County Department of Public Health’s website.

Grace Community Church did not immediately respond to CNN’s request for a comment. 

Despite the county’s public health order, which prohibits indoor services in any house of worship, Grace Community Church announced in July it would remain open to congregants for in-person worship.

Instead of listening to government or public health officials, the church said it would choose to follow “the authority of our Lord Jesus Christ.”

“We gladly choose to obey Him,” the church added.

While no further details of the outbreak or investigation were provided, the public health department said it will “work closely with the church to support outbreak management strategies that can limit transmission of COVID-19.”

Religious groups have been linked to coronavirus outbreaks in several countries, including South Korea.

Vaccine advisers urge FDA to encourage diversity in Covid-19 vaccine trials 

A sign for the Food And Drug Administration is seen outside of the agency's headquarters in White Oak, Maryland, on July 20.

Vaccine advisers are urging the US Food and Drug Administration to do as much as possible to encourage pharmaceutical companies to enroll diverse populations in their clinical trials of experimental coronavirus vaccines. 

Diversity is needed to make sure the vaccine works in the groups hardest hit by the coronavirus pandemic, and to ensure that those groups trust the vaccine enough to get it once one or more are available, members of the Vaccines and Related Biological Products Advisory Committee said at the group’s first meeting to discuss a potential Covid-19 vaccine.

Dr. Luigi Notarangelo, chief of the Laboratory of Clinical Immunology And Microbiology at the National Institute of Allergy and Infectious Diseases, said Black Americans already have a strong distrust of vaccines and drug companies. If minorities don’t enroll in vaccine trials in enough numbers, “their trust will diminish even further,” Notarangelo said.

NIAID Director Dr. Anthony Fauci has said that about 37% of the volunteers in coronavirus vaccine clinical trials should be Latino, and 27% be Black.

Vaccine maker Moderna said Thursday it has enrolled 30,000 volunteers in its coronavirus vaccine trial and says 20% of them are Latino and 10% are Black.

Vaccines and medicines can work differently in different racial and ethnic groups, so diversity in clinical trials is important.  

Black people are 2.6 times more likely to get Covid-19 than White people, and Latinos are 2.8 times more likely to get Covid-19 than White people, according to the US Centers for Disease Control and Prevention.

Greater Manchester has entered England's toughest level of lockdown restrictions

Empty tables and chairs on the eve of new Tier-3 Covid-19 restrictions in Manchester, England, on October 22.

The northern city of Manchester is now under the toughest level of coronavirus restrictions in England following the collapse of testy talks between local leaders and the national government earlier this week.

The “very high” Covid alert level – which came into force in the early hours of Friday morning local time – covers the Greater Manchester area, home to more than 2.5 million people.

The restrictions mean that people living in Greater Manchester are not allowed to socialize inside houses with anyone they do not live with, nor meet in private gardens. Outdoor social events in places like parks are limited to groups of six.

All pubs, bars, gyms, and casinos that don’t serve food must close. People can continue to visit restaurants and pubs that serve “substantial meals,” but can only eat there with people that they live with. 

In addition, Mancunians have been told to avoid all but the most essential travel outside of the Greater Manchester region. 

Convalescent plasma did not reduce Covid-19 deaths or keep patients from severe illness in new study

A bag of blood plasma from a donor who has recovered from Covid-19 is seen at The Blood and Tissue Bank Foundation in Palma de Mallorca, Spain on October 5.

In a new study, convalescent plasma did not reduce deaths among Covid-19 patients or prevent moderate disease from becoming severe.

The study, conducted in India and published in the medical journal the BMJ on Thursday, suggests that “as a potential treatment for patients with moderate Covid-19, convalescent plasma showed limited effectiveness.”

Convalescent plasma is the antibody-rich serum taken from the blood of people who recovered from Covid-19. The idea is that the plasma can help the immune response of patients still fighting the disease.

In August, the US Food and Drug Administration authorized the emergency use of convalescent plasma as a treatment option for hospitalized Covid-19 patients. However, data were still being collected in randomized controlled trials – the gold standard – to study the safety and effectiveness of the treatment.

Last month, a National Institutes of Health panel said there’s no evidence backing the use of convalescent plasma to treat coronavirus patients and that doctors should not treat it as a standard of care until more study has been done.

Read the full story:

SEATTLE, WA - APRIL 17: Phlebotomist Jenee Wilson carries COVID-19 convalescent plasma from a donor at Bloodworks Northwest on April 17, 2020 in Seattle, Washington. The plasma will be used in a new experimental treatment in hopes that the antibodies will help others still battling the COVID-19 disease. The plasma donation process, called plasmapheresis, separates blood plasma, from red and white blood cells and platelets, and returns the cells and platelets back to the donor. (Photo by Karen Ducey/Getty Images)

Related article Convalescent plasma did not reduce Covid-19 deaths or keep patients from severe illness in new study

Montana reports highest single-day number of new Covid-19 cases

Charlotte Skinner, an Emergency Room nurse at St. Peter's Health, speaks at a Covid-19 press call hosted by Gov. Steve Bullock at the State Capitol, Tuesday, Oct. 20.

Montana reported Thursday 932 new Covid-19 cases, the highest number of daily new cases since the pandemic began, according to state data.

The previous record for daily new cases, 734, was reported on Oct. 14.

Holzman added officials are also concerned about hospitals amid the increase in cases.

“A lot of the hospitals are more stressed than they usually are at this time of [the] year and that puts more panic into us, knowing that we’re now going into cold and flu season, which is the typical time of the year that hospitals see more people coming through,” Holzman said. 

Montana has reported 25,640 coronavirus cases to date and 278 total deaths.

To note: These numbers were released by the Montana Department of Health & Human Services and the state’s library and may not line up exactly in real time with CNN’s database drawn from Johns Hopkins University and the Covid Tracking Project.

White House coronavirus task force reports warn of "deterioration" in Sun Belt, Midwest and Northern states

CNN has obtained 22 state reports from the White House coronavirus task force this week. The reports show, as CNN has reported all week, a cumulative worsening of cases across the country. 

The task force is warning of surging cases in the Sun Belt, Midwest and Northern states in several reports:

New this week: the reports now show charts with hospital admission data. Next week, the reports say, there will be personal protective equipment data. 

There are at least 31 states in the task force-defined “red zone” for cases.

Here are some state-specific findings:

  • Vermont, still in the yellow zone, is the state with the lowest new case rate in the nation. There was a cluster of cases “among participants of recreational hockey and broomball leagues.” There is “cause for concern given the recent uptick in the state,” the task force warned, calling for increasing “public education about social distancing.”
  • North Dakota has the highest rate of new cases in the country. “There is no substantial improvement in North Dakota. There must be increased mitigation,” the report said.
  • The task force is sounding the alarm on “early deterioration” in gains against the virus in Alabama and said it “must be addressed aggressively as the spread is very broad based in rural and urban areas.”
  • In Louisiana, there is “very early evidence of increasing test positivity and cases.”
  • In Ohio, there is “significant reemergence of community spread.”
  • In Illinois, there is “high and worsening transmission affecting the entire state” after “sharp” increases in cases and test positivity over the last week.
  • Delaware, the task force said, “remains vulnerable” and is “at an important inflection point,” calling on the state to increase social distancing until cases decline.
  •  There is concern in Utah, which has the sixth highest case rate, about large gatherings: “Super-spreader events are still likely in areas where social distancing isn’t practiced and use of face coverings is low; impose or recommend restriction on the size of public or social gatherings to limit the ongoing possibility of such events.”
  •  Colorado, the state’s task force report said, is “at a critical juncture” that will depend on “increased observation of social distancing mitigation measures.”
  •  California and Maryland, meanwhile, won praise from the task force for “strong success with the gradated series of mitigation measures” and a “well-developed, gradated set of social distancing measures,” respectively.

Remdesivir receives FDA approval to treat hospitalized Covid-19 patients

A bottle containing the drug Remdesivir is held by a health worker at the Institute of Infectology of Kenezy Gyula Teaching Hospital of the University of Debrecen in Debrecen, Hungary, on October 15.

The antiviral remdesvir has been approved by the US Food and Drug Administration for the treatment of patients hospitalized with Covid-19, Gilead Sciences announced Thursday.

The drug, sold under the brand name Veklury, has been used under emergency use authorization (EUA) in the US. It is the first drug to be approved in the US for treating Covid-19.

Some context: Earlier this month, a World Health Organization-sponsored global study found remdesivir did not help patients survive or even recover faster, but a US study found the infused drug shortened recovery time for some patients by about a third.

Emergency approval of a Covid-19 vaccine won't stop or undermine clinical trials, FDA official says

If one of the experimental coronavirus vaccines gets emergency use authorization (EUA) from the US Food and Drug Administration, clinical trials examining the safety and efficacy of that vaccine will continue as planned, a senior FDA official said Thursday.

The FDA has said it would consider EUA for coronavirus vaccines in the works – a quicker route to getting one distributed than full approval would be. But that would mean beginning vaccination of the populace before clinical trials have finished. Some people have worried that would mean the clinical trials would end before all the data was collected.

Dr. Doran Fink, deputy director of the FDA’s division of vaccines and related products applications, said that won’t happen. Companies still will have to continue their formal clinical trials to get full licensing approval, Fink told a meeting of the FDA’s Vaccines and Related Biological Products Advisory Committee.

The FDA’s Center for Biologics Evaluation and Research does not consider the authorization of a vaccine as reason to “unblind” ongoing trials and offer the vaccine to volunteers who received a placebo, Fink said.

“CBER does not consider issuance of an EUA for a Covid-19 vaccine, in and of itself, as grounds to unblind ongoing clinical trials and offer vaccine to placebo recipients,” Fink said.

Mississippi health official: White, maskless people causing uptick in Covid-19 cases

Mississippi State Health Officer Dr. Thomas Dobbs

Dr. Thomas Dobbs, a Mississippi state health official, said that while the state’s Black communities were hit hard during the beginning of the pandemic, since the summer and fall, that trend has shifted to impact the state’s White population.

“Now it’s over 60% of new cases are in Caucasians and the deaths are mirroring that also,” Dobbs told CNN’s Brianna Keilar.

Dobbs suggested that the shift may be attributed to the African American population taking social distancing and mask measures more seriously.

“Nothing’s perfect, but the message seems have hit more fertile ground, right now, in the Black community,” he added.

Watch the full interview:

cc57cd7d-c5e9-4a8b-980d-a0fcfd331dc4.mp4
04:20 - Source: cnn

These are all the places reporting a new daily record of Covid-19 cases

People wearing face masks are seen in downtown Porto, Portugal on October 21.

Coronavirus cases continue to soar in both Europe and the United States.

There are currently at least 8,354,300 cases of Covid-19 in the US and at least 222,416 people have died from the virus, according to Johns Hopkins University’s tally of cases.

Spain reported another new daily record of Covid-19 cases on Thursday, after surpassing the grim milestone of one million coronavirus cases on Wednesday. Numbers across the continent continue to rise.

Today, many states and countries around the world reported a record high in the daily number of Covid-19 cases counted. Here’s a look at some of them.

Europe:

  • Spain reported a record 20,986 new Covid-19 cases on Thursday evening, the highest daily increase since the pandemic started. The total number of confirmed coronavirus cases in the country is now 1,026,281.
  • France reported a new record for daily coronavirus infections, with 41,622 new cases in the past 24 hours, according to numbers released by the French Health Agency. This brings the total number of confirmed cases in France to just under one million, currently at 999,043 cases.
  • Italy reported another daily record with 16,079 new coronavirus cases in the past 24 hours — up from yesterday’s record of 15,199 new cases, according to Italy’s health ministry.
  • Portugal reported a record 3,270 new Covid-19 infections on Thursday, the highest daily increase since the pandemic first reached the country.
  • Germany reported a record 11,287 new cases on Thursday, also the highest rise since the start of the pandemic.
  • The Netherlands recorded 9,283 new coronavirus cases in the last 24 hours, marking a new daily record, according to data released Thursday by the Dutch National Institute for Public Health and the Environment (RIVM).

US:

  • Oklahoma recorded 1,628 new cases — the highest daily total of new cases since the pandemic began. A total of 112,483 cases have been reported in Oklahoma so far, according to the state’s dashboard.
  • Ohio reported 2,425 new Covid-19 cases, the highest number of daily new cases since the pandemic began. The state’s previous record was reported yesterday, with 2,366 new cases.
  • Florida reported its highest daily increase of Covid-19 cases in two months, with 5,557 new cases. 
  • Wisconsin had recorded its deadliest day in coronavirus deaths, Gov. Tony Evers said. Health officials said the addition of 48 new deaths underscores the severity of the pandemic in Wisconsin. The total number of deaths from the virus in Wisconsin now stands at 1,703.

Coronavirus cases are rising in Oklahoma

More than 1,600 new Covid-19 cases were reported in Oklahoma, according to the state’s Department of Health.

The department recorded 1,628 new cases — the highest daily total of new cases since the pandemic began. A total of 112,483 cases have been reported in Oklahoma so far, according to the state’s dashboard.

At least 11 new deaths were reported, bringing the total to 1,221.  

Hospitalizations have steadily increased over the past seven days, according to the dashboard. The department said 991 patients with Covid-19 are currently hospitalized statewide.

Note: These numbers were released by Oklahoma’s public health agency and may not line up exactly in real time with CNN’s database, drawn from Johns Hopkins University and the Covid Tracking Project.

Spain reports more than 20,000 new coronavirus cases

People walk past a restaurant closed due to sharpest resurgences of the new coronavirus in Barcelona, Spain on October 22.

Spain’s health ministry reported a record 20,986 new Covid-19 cases on Thursday evening, the highest daily increase since the pandemic started. 

The total number of confirmed coronavirus cases in the country is now 1,026,281. Spain surpassed 1 million cases on Wednesday. 

The country’s death toll now stands at 34,521, with 155 new fatalities recorded today.

During a news conference Thursday evening, Fernando Simón, the director of the Spanish Center for Health Emergencies, admitted the evolution of the pandemic is not favorable. 

“We don’t know what will happen in the next few days, but yes we are going upwards,” Simón said. 

Spain’s Health Minister Salvador Illa told reporters his country is facing difficult weeks ahead. 

“There is a lot of concern, we have very tough weeks ahead,” he warned.

Illa also announced that Spain’s central government and the 17 regional governments have agreed on a document containing the main criteria for a joint response to a second wave of the pandemic. 

Utah governor warns hospitals filling up as Covid-19 cases continue to spread

Utah Gov. Gary Herbert said hospitals are “starting to fill up” in the state as Covid-19 cases continue to spread.

He said 20% of the patients currently in intensive care units are Covid-19 patients. Herbert warned that ICUs are becoming crowded.

“I would hope that people will take this seriously and do the best they can,” the governor said. 

Dr. Angela Dunn, state epidemiologist, said the state’s health care system “is at capacity.”

“I don’t know what to do anymore,” Dunn said during the briefing.

“I’m really not trying to scare anyone, I’m just trying to inform you of what’s going on and give you the facts,” she said.

Watch:

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02:10 - Source: cnn

University of Toledo halts men's basketball program following positive Covid-19 cases

Ohio’s University of Toledo announced they are pausing the men’s basketball activities for two weeks after head coach Tod Kowalczyk and six players on the team tested positive for Covid-19. 

The Rockets head coach, Tod Kowalczyk, confirmed he tested positive for the virus on Sunday. On Tuesday, the school revealed six players tested positive for Covid-19 during regular weekly surveillance testing, in compliance with NCAA Covid-19 protocols. 

According to the school, the men’s basketball program is following all university Covid-19 protocols, including isolating those who tested positive, partnering with the Toledo-Lucas County Health Department to conduct contact tracing and arranging for additional Covid-19 testing of all close contacts.

Greece imposes nighttime curfew in Athens

A medical worker collects a swab from a commuter during rapid tests for COVID-19 at a suburb in Athens, on October 22.

Greek Prime Minister Kyriakos Mitsotakis announced new restrictions Thursday to curb the spread of coronavirus. They include a nighttime curfew in high-risk areas and a mask mandate.

The nighttime curfew will be imposed in high-risk areas in an effort to limit outdoor parties and gatherings. The cities of Athens and Thessaloniki are considered high-risk areas in the country’s four tier-system along with more than a dozen other regions, including Zante and Heraklion.

Officials are seeing a significant rise in cases among young people, Mitsotakis said.

Along with the curfew, masks will now be mandatory outdoors.

The new measures will take effect at 6 a.m. local Saturday.

Mitsotakis went on to say Greece is in better shape than most European countries but warned of tough months ahead. 

Greece recorded 882 new coronavirus cases and 15 deaths on Thursday.

The country has recorded 28,216 cases and 549 deaths in total since the pandemic started, according to Greece’s National Public Health Organization.

More than 222,000 people have died from coronavirus in the US

There are at least 8,354,300 cases of coronavirus in the US and at least 222,416 people have died from the virus, according to Johns Hopkins University’s tally of cases.

So far today, Johns Hopkins has recorded 18,269 new cases and 240 reported deaths.

The totals include cases from all 50 states, the District of Columbia and other US territories, as well as repatriated cases. 

UK chief scientific adviser says widespread vaccine rollout not possible until spring 2021

UK Chief Scientific Adviser Patrick Vallance during a press conference on October 22.

Some coronavirus vaccine doses may be available before Christmas, but a widespread rollout would not be realistically possible before spring 2021, said UK Chief Scientific Adviser Patrick Vallance during a news conference on Thursday.

“Things are progressing well, there are vaccines that produce an immune response, they’re in Phase III clinical trials. .. but I remain of the view that the possibility of sort of wider spread use of vaccines isn’t going to be until spring or so next year by the time we get enough does and enough understanding of the outputs to use them,” Vallance said

Vallance also refused to speculate on how effective the vaccines are going to be and said scientists would have to wait for the results from clinical trials in the next couple of months. 

“Once we know how effective the vaccines are, and how applicable they are to different groups, we can start to work out how to use them best. But you can’t do that until you’ve seen the results of safety and efficacy,” Vallance said.

Asked about the possibility of a vaccine, British Prime Minister Boris Johnson said, “It may happen, we’re working flat out to ensure it does, but we can’t just rely on that. And that’s why we’ve got to do all the other things we’re doing.”

Johnson also pushed back on questions about another national lockdown in the UK.

“I think that really would be economically, socially, psychologically really difficult for the country. We all remember what it was like in March and April — there were lots of costs,” Johnson said. “We do think that the local measures are right. And I repeat my gratitude to local leaders across the country — people who are helping to get the R down, get the virus down in their neighborhoods.”

Bulgaria makes face coverings mandatory in public places

Passenger wear protective masks inside a tram in Sofia, Bulgaria on October 9.

As of today people in Bulgaria will be required to wear face coverings in open public places, the health ministry announced.

The measures apply when there are crowds or when people are unable to keep a physical distance of about five feet.

Exceptions will be made for customers dining in restaurants, people exercising, conference participants while speaking and children under the age of six.

Health Minister Kostadin Angelov said there will be discussions with deans of medical universities in Bulgaria around the possibility for medical students to assist doctors. 

According to Johns Hopkins University, Bulgaria recorded 1,472 new Covid-19 cases and 29 deaths in the last 24 hours – both record high figures for the country. 

To date, Bulgaria has had 33,335 Covid-19 cases, according to the country’s health ministry.

CDC to roll out cell phone-based monitoring system for Covid-19 vaccine recipients

Once a Covid-19 vaccine becomes available, the US Centers for Disease Control and Prevention plans to monitor vaccine recipients for any health problems through text messages and online surveys, as part of a new program called V-SAFE.

“V-SAFE is a new cell phone-based active surveillance program for Covid-19,” Dr. Tom Shimabukuro, deputy director of the CDC’s Immunization Safety Office, said during a US Food and Drug Administration open meeting on Thursday.

Through V-SAFE, which stands for “vaccine safety assessment for essential workers,” health checks can be conducted via text messages and email. This would happen daily in the first week after a person receives the vaccine, and then weekly thereafter for six weeks, according to the CDC’s website.

If a vaccine recipient reports any adverse events, the program will help submit a report to the US Department of Health and Human Services’ Vaccine Adverse Event Reporting System or VAERS.

“It includes active telephone follow-up,” Shimabukuro said. It’s a more active way to monitor for adverse events, instead of merely waiting for patients to report them.

Thursday’s open meeting was held to discuss the development, authorization and licensure of Covid-19 vaccines in the United States.

READ MORE

Covid-19 hospitalizations continue to rise in several states, and Wisconsin is now using an overflow facility
Coronavirus vaccine volunteer in Brazil’s AstraZeneca trial dies – but authorities say trial to continue
A Tennessee town is discouraging trick-or-treating this Halloween because of Covid-19
Vermont coronavirus cluster traced to hockey teams and a broomball league
The Czech Republic is bringing back a mask mandate that saved it from coronavirus in spring. But is it too late?

READ MORE

Covid-19 hospitalizations continue to rise in several states, and Wisconsin is now using an overflow facility
Coronavirus vaccine volunteer in Brazil’s AstraZeneca trial dies – but authorities say trial to continue
A Tennessee town is discouraging trick-or-treating this Halloween because of Covid-19
Vermont coronavirus cluster traced to hockey teams and a broomball league
The Czech Republic is bringing back a mask mandate that saved it from coronavirus in spring. But is it too late?