CNN  — 

The US could suffer 130,000 coronavirus deaths by July 4, according to a projection released Friday by the Centers for Disease Control and Prevention.

And Covid-19 cases could rise this summer as states reopen, the CDC’s deputy director for infectious diseases said during a conference call with reporters.

“If anything, we must be overprepared for what we might face later this year,” said Dr. Jay Butler. “Getting the flu vaccine will be more important than ever, as flu and Covid-19 could be circulating together as we move into the fall and winter months.”

More cities and states have reported increasing rates of new coronavirus cases per day as the nationwide total number of cases passed 2 million this week.

According to a CNN analysis of data from Johns Hopkins University, 19 states have increasing case rates, several of which have seen record or near-record highs.And for the first time, rising caseloads have led some officials to delay phased re-opening plans.

Months into the pandemic, more than 114,300 people in the US have died, according to Johns Hopkins, with about 1,000 deaths reported each day.

“We know the pandemic is not over,” Butler said.

Fauci still optimistic on vaccine chances

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said he is still confident the United States will have a coronavirus vaccine before 2021.

“By the end of the year, we will have a trial that has accrued a large number of people and we hopefully will get an answer, whether it works or not,” Fauci told CNN’s Wolf Blitzer.

There is never a guarantee a vaccine is going to be safe and effective, Fauci said. There are multiple candidates in various trials.

“But the preliminary data that we’ve seen … still indicates to me, a degree that I can have a certain amount of cautious optimism – namely, it’s inducing a response in individuals to a level that would predict that there’s a good chance that it might protect,” Fauci said about the possibility of a vaccine.

Public transit is still risky, CDC says

Also Friday, the CDC released new guidelines that say public transportation and travel can still be risky and people need to think twice before they leave home.

The public transportation guidelines, posted last month, remind people to wash their hands before and after using trains, buses, subways and other shared transport.

“During travel, try to keep at least 6 feet (2 meters) from people who are not in your household — for example, when you are waiting at a bus station or selecting seats on a train,” the guidelines read. “Wear a cloth face covering when physical distancing is difficult.”

The new guidelines also remind people about existing advice on travel.

“COVID-19 cases and deaths have been reported in all 50 states, and the situation is constantly changing. Because travel increases your chances of getting infected and spreading COVID-19, staying home is the best way to protect yourself and others from getting sick,” the CDC says.

This week’s national forecast relies on 17 individual forecasts from outside institutions and researchers. The projections forecast about 130,560 deaths by Independence Day, with a possible range of 124,260 to 139,880 deaths.

“The state-level ensemble forecasts suggest that the number of new deaths over the next four weeks in Arizona, Arkansas, Hawaii, North Carolina, Utah, and Vermont will likely exceed the number reported over the last four weeks,” the CDC says on its forecasting website.

Here’s a breakdown of some of the states that have seen rising numbers of infections.

North Carolina

North Carolina on Friday had the most cases announced in one day since the pandemic began in January.

Gov. Roy Cooper told reporters the state saw an increase of 1,768 cases reported. The percentage of positive tests also increased, he said.

Officials say they have seen four days with cases reports above 1,000 over the past week.

“The pace of the increase is concerning,” Department of Health Director Dr. Mandy Cohen said.

State health department data shows the number of hospitalizations increasing over the past 30 days.

In total, the state has reported 41,249 infections and 1,092 deaths.

Texas

Texas’s new case rates have been far higher than they were in the preceding two months, averaging 1,729 new cases per day over the week ending June 11, according to a CNN analysis of Johns Hopkins data.

A spokesman for the Texas Department of State Health Services told CNN Thursday that there were just over 2,000 new cases, warning, “This is still a serious situation.”

“People still need to be taking action to protect themselves and their communities by continuing social distancing, wearing a face covering in public, and continuing to wash their hands and disinfect surfaces frequently,” spokesman Chris Van Deusen said.

Officials in Harris County, which includes Houston, said hospitalizations are the highest to date. While they believe they can handle the rise for now, they’re preparing to re-open Houston’s NRG Stadium as a field hospital.

Florida

Meanwhile, Florida is experiencing its highest 7-day average for new cases, per Johns Hopkins data.

Gov. Ron DeSantis has said rising case numbers are due to increased testing capacity. CNN data shows statewide testing rose, dropped and is now rising again.

Dr. Aileen Marty, an infectious disease expert at Florida International University in Miami said a “small part” of the increase was testing, “but it truly is a real increase in cases.” That rise could be exacerbated by people not wearing masks or social distancing, Marty said, and by the use of tear gas at recent protests following the police killing of George Floyd in Minneapolis.

“The use of these gases is very serious … because it damages the airways,” Marty said. “It damages the exact airways that our bodies need to fend off this virus.”

Arizona

Arizona Gov. Doug Ducey said Thursday the state had the hospital capacity to deal with a recent spike in cases, adding it was not serious enough to reestablish economic restrictions.

According to the state, Arizona hit a peak of 79% of intensive care hospital beds in use on Tuesday, while the use of ventilators rose to an all-time high of 38% on Wednesday.

Ducey said the hospital bed rate does not include an additional 2,600 “surge” beds set aside in the event of a dramatic rise.

The mayor of Phoenix, however, said the state is not recovering from Covid-19.

“We have had so many of the records you don’t want to be hitting for Covid-19 from my perspective,” Mayor Kate Gallego said at a panel discussion with other mayors hosted by the Center for American Progress. “We opened too much too early and so our hospitals are really struggling.”

Gallego attributed the spike primarily to the lifting of the state’s stay-at-home order on May 15.

California

In California, Los Angeles hit a near-record high in cases, even as the county moves toward Phase 3 of its re-opening plan on Friday, allowing businesses like gyms, museums, day camps and TV production to resume operations.

Los Angeles County reported 1,857 new cases on Thursday, the second-highest number reported in one day.A news release noted that 600 of those cases were from a backlog of test results.

On Wednesday, Los Angeles Mayor Eric Garcetti conceded that business reopening makes him “nervous.”

“We are still in the biggest medical pandemic of our lives,” he said, urging those who participate in protests to quarantine for 14 days or get a Covid-19 test.

CNN’s Shelby Lin Erdman, Jacqueline Howard, Michael Nedelman, Arman Azad, Maggie Fox, Jamiel Lynch, Jay Croft, Ethan Cohen and Andy Rose contributed to this report.