Global novel coronavirus death toll reaches 1,383 as China purges officials in Hubei

The number of novel coronavirus cases has risen to more than 64,000 worldwide, after China reported another major increase at the epicenter of the outbreak following a change in how authorities there diagnose cases.

As of Friday morning, over 100 more people had died of the virus, officially known as Covid-19, in central China’s Hubei province – raising the global death toll to 1,383. Of those, all but three have died in mainland China.

Chinese health authorities also confirmed an additional 5,090 cases across the country. That’s a major spike, but nowhere near the 14,840 new cases reported Thursday – the largest single-day rise since the epidemic began.

The government explained the spike was due to a change in how cases are tabulated – the total will now include “clinically diagnosed cases” – people who demonstrate all the symptoms of Covid-19 but have either been unable to access a test or are believed to have falsely tested negative. The hope is that more people will be able to receive treatment by receiving this diagnosis.

The health system in Hubei, particularly in the capital Wuhan where the outbreak began, has struggled to handle the influx of patients, even with the help of several purpose-built hospitals dedicated to treating Covid-19. Provincial authorities said there are about 37,000 patients in hospital, 1,685 of whom are in critical condition.

More than 6,723 patients in China have recovered and been discharged since the outbreak began.

Medical staff wearing protective suits ride down an escalator at Moscow's Sheremetyevo International Airport on Wednesday, March 18.

Hasidic Jewish men take part in a "social distancing" minyan in New York on Tuesday, March 17.

A patient in a biocontainment unit is carried on a stretcher in Rome on March 17.

A pedestrian walks a dog through a quiet street in New York on March 17.

People gather to collect free face masks in New Delhi on March 17.

Dermot Hickey, left, and Phillip Vega ask a pedestrian in New York to take their picture on a thinly trafficked Fifth Avenue on March 17. Many streets across the world are much more bare as people distance themselves from others. In the United States, the White House has advised people not to gather in groups of more than 10.

Students at the Attarkiah Islamic School wear face masks during a ceremony in Thailand's southern province of Narathiwat on March 17.

People wait outside a Woolworths store in Sunbury, Australia on March 17. Australian supermarket chains announced special shopping hours for the elderly and people with disabilities so that they can shop in less crowded aisles.

A member of Spain's Military Emergencies Unit carries out a general disinfection at the Malaga airport on Monday, March 16.

Displaced families near Atme, Syria, attend a workshop aimed at spreading awareness about the coronavirus.

French President Emmanuel Macron is seen on a screen in Paris as he announces new coronavirus containment measures on March 16. France has been put on lockdown, and all nonessential outings are outlawed and can draw a fine of up to €135 ($148). Macron also promised to support French businesses by guaranteeing €300 billion worth of loans and suspending rent and utility bills owed by small companies.

A police officer checks the temperatures of bus passengers at a checkpoint in Manila, Philippines, on March 16.

Flowers are stored prior to their destruction at a flower auction in Aalsmeer, Netherlands, on March 16. Lower demand due to the coronavirus outbreak is threatening the Dutch horticultural sector, forcing the destruction of products.

Two nuns greet neighbors from their balcony in Turin, Italy, on Sunday, March 15.

Pope Francis, inside the Church of San Marcello in Rome's city center, prays at a famous crucifix that believers claim helped to save Romans from the plague in 1522.

Passengers wait for their flights at Marrakesh Airport in Morocco on March 15.

US Vice President Mike Pence takes a question during a White House briefing about the coronavirus on March 15.

A Sea World employee sprays disinfectant in Jakarta, Indonesia, on Saturday, March 14.

People wait in line to go through customs at Dallas/Fort Worth International Airport on March 14. Travelers returning from Europe say they were being made to wait for hours at US airports, often in close quarters, as personnel screened them for the coronavirus.

Hundreds of people lined up to enter a Costco in Novato, California, on March 14. Many people have been stocking up on food, toilet paper and other items. As a response to panic buying, retailers in the United States and Canada have started limiting the number of toilet paper that customers can buy in one trip.

A member of the White House physician's office takes a media member's temperature in the White House briefing room on March 14. It was ahead of a news conference with President Donald Trump and Vice President Mike Pence.

Reporters in Arlington, Virginia, sit approximately 4 feet apart during a briefing by Marine Corps Gen. Kenneth F. McKenzie on Friday, March 13.

People walk past a closed Broadway theater on March 13 after New York canceled all gatherings over 500 people.

Body temperatures are scanned as people enter the Buddhist temple Wat Pho in Bangkok, Thailand, on March 13.

A Costco customer stands by two shopping carts in Richmond, California, on March 13.

A teacher works in an empty classroom at the Pompeu Fabra University in Barcelona, Spain.

A woman looks at an empty bread aisle in Antwerp, Belgium, on March 13.

Employees of the Greek Parliament wear plastic gloves ahead of the swearing-in ceremony for Greek President Katerina Sakellaropoulou.

A motorcyclist drives through disinfectant sprayed in Jammu, India, on March 13.

Workers prepare to construct an additional building on a hospital on the outskirts of Moscow.

Paul Boyer, head equipment manager of the NHL's Detroit Red Wings, wheels out equipment bags in Washington on Thursday, March 12. The NHL is among the sports leagues that have suspended their seasons.

Students leave Glacier Peak High School in Snohomish, Washington, on March 12. Beginning the following day, schools in the Snohomish school district planned to be closed through April 24.

An Uber Eats delivery biker stands at a deserted Piazza di Spagna in Rome.

People at a railway station in Seoul, South Korea, watch a live broadcast of US President Donald Trump on March 12. Trump announced that, in an effort to slow the spread of the coronavirus, he would sharply restrict travel from more than two dozen European countries.

Workers in protective suits disinfect Istanbul's Dolmabahce Palace on March 11.

A person wearing a face mask walks outside of a shopping mall in Beijing on March 11.

Police officers restrain the relative of an inmate outside the Sant'Anna jail in Modena, Italy, on March 9. Riots broke out in several Italian jails after visits were suspended to curb the spread of the coronavirus.

Medical staff in Wuhan, China, celebrate after all coronavirus patients were discharged from a temporary hospital on March 9.

Traders work on the floor of the New York Stock Exchange on March 9. Stocks plummeted as coronavirus worries and an oil price race to the bottom weighed on global financial markets.

Rescuers search for victims at the site of a collapsed hotel in Quanzhou, China, on March 8. The hotel was being used as a coronavirus quarantine center.

The Grand Princess cruise ship, carrying at least 21 people who tested positive for coronavirus, is seen off the coast of San Francisco on March 8. The ship was being held at sea.

Sumo wrestlers attend a tournament in Osaka, Japan, that was being held behind closed doors because of the coronavirus outbreak.

A couple rides a bicycle at a park in Seoul, South Korea, on March 7.

A volunteer from Blue Sky Rescue uses fumigation equipment to disinfect a residential compound in Beijing on March 5.

Airmen from the California National Guard drop coronavirus testing kits down to the Grand Princess cruise ship off the coast of California on March 5.

Municipal workers are seen at the Kaaba, inside Mecca's Grand Mosque. Saudi Arabia emptied Islam's holiest site for sterilization over coronavirus fears, an unprecedented move after the kingdom suspended the year-round Umrah pilgrimage.

Passengers react as a worker wearing a protective suit disinfects the departure area of a railway station in Hefei, China, on March 4.

Teachers at the Nagoya International School in Japan conduct an online class for students staying at home as a precaution against the spread of coronavirus.

Soldiers spray disinfectant throughout a shopping street in Seoul.

A Muslim worshipper attends a mass prayer against coronavirus in Dakar, Senegal, on March 4. It was after cases were confirmed in the country.

People wear face masks in New York's Times Square on March 3. New York reported its first case of coronavirus two days earlier.

A security guard stands on the Shibuya Sky observation deck in Tokyo on March 3.

US President Donald Trump, flanked by Vice President Mike Pence, left, and Health and Human Services Secretary Alex Azar, speaks during a meeting with pharmaceutical executives and the White House coronavirus task force on March 2. Throughout the meeting, Trump was hyperfocused on pressing industry leaders in the room for a timeline for a coronavirus vaccine and treatment. But experts at the table -- from the administration and the pharmaceutical industry -- repeatedly emphasized that a vaccine can't be rushed to market before it's been declared safe for the public.

Medical staff stand outside a hospital in Daegu, South Korea, on March 1.

Healthcare workers transfer a patient at the Life Care Center in Kirkland, Washington, on March 1. The long-term care facility is linked to confirmed coronavirus cases.

British Prime Minister Boris Johnson visits a London laboratory of the Public Health England National Infection Service.

Tomoyuki Sugano, a professional baseball player on the Yomiuri Giants, throws a pitch in an empty Tokyo Dome during a preseason game on February 29. Fans have been barred from preseason games to prevent the spread of the coronavirus.

Commuters wearing masks make their way to work during morning rush hour at the Shinagawa train station in Tokyo on February 28.

Medical staff transport a coronavirus patient within the Red Cross hospital in Wuhan on February 28.

Inter Milan plays Ludogorets in an empty soccer stadium in Milan, Italy, on February 27. The match was ordered to be played behind closed doors as Italian authorities continue to grapple with the coronavirus outbreak.

A bank clerk disinfects banknotes in China's Sichuan province on February 26.

A child wearing a protective face mask rides on a scooter in an empty area in Beijing.

A Catholic devotee wears a face mask as he is sprinkled with ash during Ash Wednesday services in Paranaque, Philippines, on February 26.

People disinfect Qom's Masumeh shrine in Tehran, Iran, on February 25.

A worker in Daegu stacks plastic buckets containing medical waste from coronavirus patients on February 24.

Paramedics carry a stretcher off an ambulance in Hong Kong on February 23.

People attend a professional soccer match in Kobe, Japan, on February 23. To help stop the spread of the novel coronavirus, the soccer club Vissel Kobe told fans not to sing, chant or wave flags in the season opener against Yokohama FC.

A team of volunteers disinfects a pedestrian bridge in Bangkok, Thailand.

A man rides his bike in Beijing on February 23.

Hospital personnel in Codogno, Italy, carry new beds inside the hospital on February 21. The hospital is hosting some people who have been diagnosed with the novel coronavirus.

Doctors look at a CT scan of a lung at a hospital in Xiaogan, China, on February 20.

A sales clerk wears a mask as she waits for customers at a hat shop in Beijing on February 18. Small companies that help drive China's economy are worried about how much damage the coronavirus outbreak will cause to business.

Buses carrying American passengers arrive at the Haneda Airport in Tokyo on February 17. The passengers were leaving the quarantined Diamond Princess cruise ship to be repatriated to the United States.

A medical worker rests at the isolation ward of the Red Cross hospital in Wuhan on February 16.

Authorities watch as the Westerdam cruise ship approaches a port in Sihanoukville, Cambodia, on February 13. Despite having no confirmed cases of coronavirus on board, the Westerdam was refused port by four other Asian countries before being allowed to dock in Cambodia.

A worker has his temperature checked on a shuttered commercial street in Beijing on February 12.

Beds are made in the Wuhan Sports Center, which has been converted into a temporary hospital.

A child rides a scooter past a police officer wearing protective gear outside the Hong Mei House in Hong Kong on February 11. More than 100 people evacuated the housing block after four residents in two different apartments tested positive for the coronavirus.

Relatives of quarantined passengers wave at the Diamond Princess cruise ship as it leaves a port in Yokohama, Japan, to dump wastewater and generate potable water. Dozens of people on the ship were infected with coronavirus.

The Deneway branch of the County Oak Medical Centre is closed amid coronavirus fears in Brighton, England, on February 11. Several locations in and around Brighton were quarantined after a man linked to several coronavirus cases in the United Kingdom came into contact with health-care workers and members of the public.

A police officer, left, wears protective gear as he guards a cordon at the Hong Mei House in Hong Kong on February 11.

A worker wears a protective suit as he waits to screen people entering an office building in Beijing on February 10. China's workforce is slowly coming back to work after the coronavirus outbreak forced many parts of the country to extend the Lunar New Year holiday by more than a week.

Chinese President Xi Jinping has his temperature checked during an appearance in Beijing on February 10.

Photojournalists wearing face masks take photos of a bus carrying passengers after they disembarked from the World Dream cruise ship in Hong Kong on February 9. More than 5,300 people were quarantined on two cruise ships off Hong Kong and Japan.

People participating in a Lunar New Year Parade in New York City hold signs reading, "Wuhan stay strong!" on February 9.

A shopper walks past empty shelves at a grocery store in Hong Kong on February 9. China's Ministry of Commerce encouraged supermarkets and grocery stores to resume operations as the country's voluntary or mandatory quarantines began to take an economic toll.

A worker wearing a protective suit uses a machine to disinfect a business establishment in Shanghai, China, on February 9.

Workers in protective gear walk near the Diamond Princess cruise ship docked in Yokohama on February 7.

People in Hong Kong attend a vigil February 7 for whistleblower doctor Li Wenliang. Li, 34, died in Wuhan after contracting the virus while treating a patient.

A woman grieves while paying tribute to Li at Li's hospital in Wuhan on February 7.

The Anthem of the Seas cruise ship is seen docked at the Cape Liberty Cruise Port in Bayonne, New Jersey, on February 7. Passengers were to be screened for coronavirus as a precaution, an official with the Centers for Disease Control and Prevention told CNN.

A light installation is displayed by striking members of the Hospital Authority Employees Alliance and other activists at the Hospital Authority building in Hong Kong on February 7.

Passengers are seen on the deck of the Diamond Princess cruise ship, docked at the Yokohama Port on February 7.

Flight attendants wearing face masks make their way through Don Mueang Airport in Bangkok on February 7.

Workers check sterile medical gloves at a latex-product manufacturer in Nanjing, China, on February 6.

A woman wears a protective mask as she shops in a Beijing market on February 6.

This aerial photo shows the Leishenshan Hospital that is being built in Wuhan to handle coronavirus patients.

A passenger shows a note from the World Dream cruise ship docked at the Kai Tak cruise terminal in Hong Kong on February 5.

A mask is seen on a statue in Beijing on February 5.

An ambulance stops at a traffic light in front of the Grand Lisboa Hotel in Macao. The virus turned China's gambling mecca into a ghost town.

A dog in Beijing wears a makeshift mask constructed from a paper cup.

Striking hospital workers in Hong Kong demand the closure of the border with mainland China on February 4.

The Diamond Princess cruise ship sits anchored in quarantine off the port of Yokohama on February 4. It arrived a day earlier with passengers feeling ill.

A medical worker wearing protective gear waits to take the temperature of people entering Princess Margaret Hospital in Hong Kong on February 4.

Medical workers in protective suits help transfer patients to a newly completed field hospital in Wuhan.

People wearing protective overalls talk outside a Wuhan hotel housing people in isolation on February 3.

A man stands in front of TV screens broadcasting a speech by Hong Kong Chief Executive Carrie Lam on February 3. Lam said the city would shut almost all border-control points to the mainland.

A colleague sprays disinfectant on a doctor in Wuhan on February 3.

Commuters in Tokyo walk past an electric board displaying dismal stock prices on February 3, the first business day after the Chinese New Year. Asia's markets recorded their worst day in years as investors finally got a chance to react to the worsening coronavirus outbreak.

Medical workers move a coronavirus patient into an isolation ward at the Second People's Hospital in Fuyang, China, on February 1.

Children wear plastic bottles as makeshift masks while waiting to check in to a flight at the Beijing Capital Airport on January 30.

Passengers in Hong Kong wear protective masks as they wait to board a train at Lo Wu Station, near the mainland border, on January 30.

A volunteer wearing protective clothing disinfects a street in Qingdao, China, on January 29.

Nanning residents line up to buy face masks from a medical appliance store on January 29.

Lyu Jun, left, a member of a medical team leaving for Wuhan, says goodbye to a loved one in Urumqi, China, on January 28.

A charter flight from Wuhan arrives at an airport in Anchorage, Alaska, on January 28. The US government chartered the plane to bring home US citizens and diplomats from the American consulate in Wuhan.

South Korean President Moon Jae-in wears a mask to inspect the National Medical Center in Seoul on January 28.

Hong Kong Chief Executive Carrie Lam, center, attends a news conference in Hong Kong on January 28. Lam said China will stop individual travelers to Hong Kong while closing some border checkpoints and restricting flights and train services from the mainland.

Workers at an airport in Novosibirsk, Russia, check the temperatures of passengers who arrived from Beijing on January 28.

Alex Azar, the US Secretary of Health and Human Services, speaks during a news conference about the American public-health response.

Two residents walk in an empty park in Wuhan on January 27. The city remained on lockdown for a fourth day.

A person wears a protective mask, goggles and coat as he stands in a nearly empty street in Beijing on January 26.

Medical staff members bring a patient to the Wuhan Red Cross hospital on January 25.

People wear protective masks as they walk under Lunar New Year decorations in Beijing on January 25.

Construction workers in Wuhan begin to work on a special hospital to deal with the outbreak on January 24.

Dr. Allison Arwady, commissioner of the Chicago Department of Public Health, speaks to reporters on January 24 about a patient in Chicago who had been diagnosed with the coronavirus. The patient was the second in the United States to be diagnosed with the illness.

A couple kisses goodbye as they travel for the Lunar New Year holiday in Beijing on January 24.

Workers manufacture protective face masks at a factory in China's Hubei Province on January 23.

Shoppers wear masks in a Wuhan market on January 23.

Passengers are checked by a thermography device at an airport in Osaka, Japan, on January 23.

People wear masks while shopping for vegetables in Wuhan on January 23.

A militia member checks the body temperature of a driver in Wuhan on January 23.

Passengers wear masks as they arrive at the Ninoy Aquino International Airport in Manila, Philippines, on January 23.

A customer holds boxes of particulate respirators at a pharmacy in Hong Kong on January 23.

Passengers wear masks at the high-speed train station in Hong Kong on January 23.

A woman rides an electric bicycle in Wuhan on January 22.

People in Guangzhou, China, wear protective masks on January 22.

People go through a checkpoint in Guangzhou on January 22.

Medical staff of Wuhan's Union Hospital attend a gathering on January 22.

Health officials hold a news conference in Beijing on January 22.

In pictures: The novel coronavirus outbreak

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Beijing purge

As the number of deaths and cases at the epicenter of the outbreak continued to rise, China moved to purge several officials in the region, replacing them with loyalists of Chinese President Xi Jinping, who has now taken personal charge of the response.

State media announced Thursday that the Communist Party chiefs of Hubei and Wuhan had both been removed. Ying Yong, the former mayor of Shanghai, will become the new Hubei chief, while Wang Zhonglin will take over Wuhan itself. Ying is a key protege of Xi’s, and the two men have worked together since the early 2000s when they were both officials in the eastern province of Zhejiang.

Another Zhejiang veteran and Xi ally, Chen Yixin, is already in Wuhan. Chen arrived in the city last week to lead the response to the epidemic – his appointment there was seen as Xi moving to take charge of the crisis after it was mishandled in the early weeks by Wuhan and Hubei officials, who have been accused of downplaying the severity of the virus, resulting in its spread nationwide.

The removal of the Wuhan and Hubei party chiefs might only be the beginning of the provincial purge. Last week, amid nationwide outrage over the death of whisteblower doctor Li Wenliang – who was reprimanded for spreading “rumors” by Wuhan police – Beijing dispatched an anti-corruption team to the city to investigate the matter.

Wuhan Mayor Zhou Xianwang, one of the public faces of the crisis, previously offered to resign “to appease public indignation,” but the central government has yet to take him up on that.

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Worldwide spread

While the vast majority of Covid-19 are in mainland China, the virus has been confirmed in more than two dozen countries worldwide, and concern is growing over its potential spread outside the epicenter.

“This outbreak could still go in any direction,” World Health Organization director general Tedros Adhanom Ghebreyesus said Wednesday.

“We have to invest in preparedness,” Tedros said, adding that richer countries should help invest in countries with a weaker health system. He warned the virus could “create havoc” if it reaches a country whose health system is not capable of handling such an epidemic.

Three additional cases were confirmed in Hong Kong as of Friday morning, bringing the total to 53 in the semi-autonomous Chinese city, which has been in partial shutdown for weeks and closed most of its borders with the mainland. One of the three deaths outside mainland China occurred in the city.

YOKOHAMA, JAPAN - FEBRUARY 10: Members of Japans self-defence forces place tarpaulin over a walkway to a miltary truck from the Diamond Princess cruise ship at Daikoku Pier where it is being resupplied and newly diagnosed coronavirus cases taken for treatment as it remains in quarantine after a number of the 3,700 people on board were diagnosed with coronavirus, on February 10, 2020 in Yokohama, Japan. 70 passengers are now confirmed to be infected with coronavirus as Japanese authorities continue treating people on board. The new cases bring the total number of confirmed infections to 96 in Japan, the largest number outside of China. (Photo by Carl Court/Getty Images)

Related article Worker on board Diamond Princess says crew are at greater risk of coronavirus

The third of those deaths occurred in Japan on Thursday – a woman in her 80s, according to health officials. She was not a passenger on board the Diamond Princess cruise liner currently quarantined at Yokohama, south of Tokyo.

The ship is currently home to the largest outbreak outside mainland China. Another 44 cases of the virus were confirmed Thursday, bringing the total of cases on the ship to 219, as Japanese health authorities continue to test the more than 3,500 people on board.

Japanese health minister Katsunobu Kato said that people who had tested negative for the virus and were over 80 years old, or had a non-virus medical condition requiring attention, would be allowed to leave the ship and move to a government medical facility. He did not give a timeline for that process. Already on Tuesday, an unknown number of passengers with non-virus medical conditions had been allowed to disembark.

Frustration is growing, however, among the thousands passengers and crew on board, who have been unable to leave the ship for a week now.

Speaking to CNN, one crew member said she feared the crew were at greater risk of being exposed to the outbreak because they were not being quarantined in the same way as the passengers and were having to continue working to take care of the guests.

Sonali Thakkar, 24, from Mumbai, said she and her colleague – who she shares a cabin with – became ill with a headache, cough and a fever two days ago. Her supervisor told her to stop working and she is currently staying in her cabin in isolation.

“I’m not eating very well and have been having fevers,” she told CNN in a Skype call Wednesday. “We all are really scared and tense.”

Thakkar feared that the virus may be spreading around the crew. At least five have tested positive.

There was better news for passengers on board MS Westerdam, another cruise ship. After several days in limbo at sea due to ports not being willing to accept it – despite no coronavirus cases being confirmed on board – it was finally able to dock in Cambodia Friday, where passengers were greeted by Prime Minister Hun Sen.

CNN’s Ben Tinker in Atlanta; Steven Jiang and Yong Xiong in Beijing; Mick Krever in Yokohama; Helen Regan, Carly Walsh, Laura He, Isaac Yee, Sandi Sidhu and Nectar Gan in Hong Kong; and Lindsay Isaac, Zahid Mahmood and Meera Senthilingam in London contributed reporting.