Live from New York, it’s Donald Trump!

Republican presidential candidate Donald Trump is set to host NBC’s “Saturday Night Live” on November 7.

This will be the businessman’s second time hosting the network’s iconic sketch show – he first hosted in 2004, while serving as the host of the NBC reality show “The Apprentice.”

The Donald’s relationship with SNL is unique and long-running. He and his wife Melania walked the red carpet at SNL’s 40th anniversary show in February.

He’s also been a consistent character — played by some of the show’s most famous cast members — for more than two decades, even before his career in television and shift to politics. During the late 1980s, Phil Hartman was the first cast member to regularly play Trump. Darrell Hammond played Trump for more than a decade, and Taran Killam took the reins this season.

Actress Kate McKinnon recently caught the notice of the political and entertainment worlds with her parody of Hillary Clinton on "Saturday Night Live." The two even appeared together in an October sketch. Click through to see the storied history of "SNL" and political parody.

Actress Amy Poehler also played Clinton in several "SNL" skits.

Actors Taran Killam and Cecily Strong revealed their impersonations of Republican presidential candidate Donald Trump and his wife, Melania, on a "Saturday Night Live" episode in October.

Larry David may have been born to play Bernie Sanders. The "Curb Your Enthusiasm" star played the presidential candidate in a skit that was a parody of the CNN Democratic debate. David received favorable reviews of his depiction of the presidential candidate.

President Bill Clinton laughs with lookalike Darrell Hammond at the annual dinner of the Radio and Television Correspondents' Association in 1997. Hammond portrayed Clinton on "Saturday Night Live."

Actress Tina Fey's parody of Sarah Palin became a favorite during the 2008 presidential election.

Actors Fred Armisen and Jason Sudeikis impersonated President Barack Obama and Vice President Joe Biden in a 2009 skit.

"Saturday Night Live" often mocks presidential debates soon after they happened. Jason Sudeikis and Jay Pharoah portrayed Mitt Romney and Obama in 2012.

"Saturday Night Live" aired its own presidential debate for the 2004 election with Seth Meyers as John Kerry and Will Forte as President George W. Bush.

Politicians and their 'SNL' alter egos

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Trump’s adult children and all three of his wives have been characters on the show as well.

Franken predicts ‘entertaining’ Trump on ‘SNL’

During his last hosting gig, Trump embraced SNL’s portrayal by endorsing Hammond’s performance during his opening monologue. He went on to play himself in a few sketches, living up to the out of touch, ratings-crazed, power-hungry, borderline-delusional character that the show’s audience had come to expect.

While most major presidential candidates and political figures are lampooned by the show’s cast, it’s rarer for politicians to play themselves. President George H.W. Bush appeared on the show after leaving office, then-Senator Barack Obama made a cameo during the 2008 campaign cycle, and current Democratic front-runner Hillary Clinton played a bartender on the show last month.

Opinion: ‘SNL’ and Trump face a HUGE challenge